Replication of Marek's disease virus in cell cultures derived from genetically resistant chickens.

Responses of isolator-derived Japanese quail and quail cell cultures to selected animal viruses.

Thirteen oncogenic and necrotizing animal viruses were assayed in LIFE Sciences, Inc. (LSI)-specific pathogen-free Japanese quail and LSI-specific pathogen-free chicken embryo cell cultures. Nine viruses produced similar titers in the quail and chicken cell systems, whereas four viruses showed significantly higher titers in chickens. Young Japanese quail and chickens were inoculated with five s...

Inhibitory effects of nitric oxide and gamma interferon on in vitro and in vivo replication of Marek's disease virus.

The replication of Marek's disease herpesvirus (MDV) and herpesvirus of turkeys (HVT) in chicken embryo fibroblast (CEF) cultures was inhibited by the addition of S-nitroso-N-acetylpenicillamine, a nitric oxide (NO)-generating compound, in a dose-dependent manner. Treatment of CEF culture, prepared from 11-day-old embryos, with recombinant chicken gamma interferon (rChIFN-gamma) and lipopolysac...

Recombinant Marek’s disease virus type 1 provides full protection against very virulent Marek’s and infectious bursal disease viruses in chickens

Marek's disease virus (MDV) is a preferred vector in the construction of recombinant vaccines. However, bivalent vaccine based on MDV that confers full protection against both very virulent Marek's and infectious bursal disease virus (IBDV) infections in chickens has not been produced. Here we developed a system utilizing overlapping fosmid DNAs transfection that rescues an MDV type 1 (MDV1) va...

Immune response of chickens to four lentogenic strains of Newcastle disease virus propagated in lamb kidney cell cultures

Levels of Minerals in Sera of Chickens Suffering from Marek's Disease

Jurajdova J.: Levels of Minerals in Sera of Chickens Suffering from Marek's Disease. Acta vet. Brno, 47, 1978: 189-196. The concentrations were studied of sodium, potassium, calcium, magnesium and phosphorus as well as the correlations and coefficients of their level ratios in sera of RIR chickens 56 days after infection with Marek's disease virus, and they were compared with the controls. In t...